The Heat-Inactivation of Diphtheria Antitoxin

Xlvii. the Heat Inactivation of Diphtheria Antitoxin

Studies of Diphtheria Antitoxin in Rheumatic Fever

The importance of group A hemolytic streptococcal infections in the pathogenesis of rheumatic fever is widely recognized, but little is known of the mechanism by which the streptococcal infection gives rise to the disease. The concept that an antigen-antibody interaction may be involved in the origin of the pathologic processes has received increasing attention, and recent antibody studies (1, ...

Purification and Crystallization of Diphtheria Antitoxin

Purified preparations of diphtheria antitoxin have been obtained by digestion of the toxin-antitoxin complex with trypsin, followed by fractional precipitation with ammonium sulfate. The various fractions obtained in this way are all 90 per cent or more precipitated by diphtheria toxin but combine with different quantities of the toxin. The fraction precipitated between 0.33 and 0.5 saturated a...

The distribution of diphtheria antitoxin in pepsin-digested horse antiserum.

Diphtheria antitoxin levels in the Netherlands: a population-based study.

In a population-based study in the Netherlands, diphtheria antitoxin antibodies were measured with a toxin-binding inhibition assay in 9, 134 sera from the general population and religious communities refusing vaccination. The Dutch immunization program appears to induce long-term protection against diphtheria. However, a substantial number of adults born before the program was introduced had n...